:root{font-family:Inter,ui-sans-serif,system-ui,-apple-system,BlinkMacSystemFont,"Segoe UI",Tahoma,sans-serif;color:#142236;background:#f3f6fa;line-height:1.5;--navy:#0b2c55;--blue:#145da0;--red:#c72535;--border:#d9e2ec;--muted:#627386;--card:#fff;--ok:#18794e;--warn:#9a6700;--danger:#b42318}
*{box-sizing:border-box}body{margin:0}.hidden{display:none!important}.loading{min-height:100vh;display:grid;place-items:center;font-size:1.05rem;color:#334e68}.topbar{background:linear-gradient(120deg,#fff 0,#f7fbff 55%,#e7f1fb 100%);padding:18px clamp(18px,4vw,54px);display:flex;justify-content:space-between;gap:24px;align-items:center;border-bottom:1px solid #cfdbe8}.brand-wrap{display:flex;align-items:center;gap:18px}.logo-box{background:#fff;border-radius:12px;padding:7px 12px;box-shadow:0 1px 4px rgba(11,44,85,.08)}.logo-box img{display:block;width:230px;max-width:38vw;height:auto}.eyebrow{font-size:.78rem;text-transform:uppercase;letter-spacing:.08em;color:#5f7084;font-weight:700}.topbar h1{margin:.1rem 0 0;color:var(--navy);font-size:clamp(1.45rem,3vw,2.25rem)}.prod-badge{border:1px solid #9eb7d1;background:#fff;color:var(--navy);padding:9px 13px;border-radius:10px;text-align:center;font-weight:800;line-height:1.15}.prod-badge span{font-size:.7rem;color:#526a82}.tabs{display:flex;gap:6px;padding:10px clamp(12px,3vw,42px);background:#fff;border-bottom:1px solid var(--border);overflow:auto;position:sticky;top:0;z-index:10}.tabs button{border:0;background:transparent;padding:10px 14px;border-radius:8px;font-weight:700;white-space:nowrap;color:#334e68;cursor:pointer}.tabs button.active{background:#eaf2fb;color:var(--navy)}main{max-width:1480px;margin:0 auto;padding:22px clamp(12px,3vw,38px) 50px}.card{background:var(--card);border:1px solid var(--border);border-radius:14px;padding:20px;box-shadow:0 2px 9px rgba(20,45,75,.04)}.card h2{margin-top:0}.section-title{font-size:1rem;font-weight:800;color:var(--navy);border-bottom:1px solid #e5edf5;padding-bottom:7px;margin:18px 0 12px}.form-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:12px}.three-col{grid-template-columns:repeat(3,minmax(0,1fr))}.two-col-grid{grid-template-columns:repeat(2,minmax(0,1fr))}.field{display:flex;flex-direction:column;gap:5px;font-size:.9rem}.field span{font-weight:700;color:#334e68}.field b{color:var(--red)}input,select{width:100%;padding:10px 11px;border:1px solid #bcccdc;border-radius:8px;background:#fff;color:#102a43;font:inherit}input:focus,select:focus{outline:2px solid #8ec5ff;outline-offset:1px}select:disabled,input:disabled{background:#f3f5f7;color:#8a99a8}.button-row{display:flex;flex-wrap:wrap;gap:8px;margin-top:18px}button,.file-button{font:inherit;cursor:pointer}.primary,.secondary,.danger-button,.file-button,.link-button{border-radius:8px;padding:9px 13px;border:1px solid transparent;font-weight:700;text-decoration:none;display:inline-flex;align-items:center;justify-content:center}.primary{background:var(--navy);color:#fff}.primary:disabled{opacity:.45;cursor:not-allowed}.secondary{background:#eef4fa;color:#163b66;border-color:#cbd9e8}.file-button{background:#eef4fa;color:#163b66;border-color:#cbd9e8}.file-button input{display:none}.context-box{margin:14px 0;background:#f6f9fc;border:1px solid #cbd9e8;border-radius:10px;padding:14px}.micro{font-size:.76rem;color:var(--muted);margin-top:3px}.muted{color:var(--muted)}.danger{color:var(--danger)!important}.success-text{color:var(--ok)!important}.warning-text{color:var(--warn)!important}.alert{padding:10px 12px;border-radius:9px;margin:10px 0;font-size:.9rem}.alert-warning{background:#fff8db;border:1px solid #eadb92;color:#674d00}.alert-error{background:#fff1f1;border:1px solid #efb5b5;color:#7f1d1d}.alert-success{background:#edf9f3;border:1px solid #a8dfc5;color:#14532d}.alert-info{background:#eef6ff;border:1px solid #bfd8f2;color:#174f7a}.output-card{margin-top:18px}.result-header{display:grid;grid-template-columns:repeat(3,1fr);gap:10px;margin-bottom:14px}.result-header>div{background:#f6f9fc;padding:12px;border-radius:10px;display:flex;flex-direction:column}.kpi-label{font-size:.75rem;color:var(--muted);text-transform:uppercase;letter-spacing:.04em}.table-wrap{overflow:auto;border:1px solid var(--border);border-radius:10px}table{width:100%;border-collapse:collapse;min-width:900px}th,td{text-align:left;padding:10px 11px;border-bottom:1px solid #e8eef4;vertical-align:top;font-size:.87rem}th{background:#f6f9fc;color:#334e68}.badge{display:inline-block;padding:3px 8px;border-radius:999px;font-size:.68rem;font-weight:800;letter-spacing:.03em}.badge-ok{background:#e7f7ef;color:#146c43}.badge-warning{background:#fff4cc;color:#795700}.badge-neutral{background:#edf2f7;color:#425466}.section-heading{display:flex;justify-content:space-between;align-items:end;gap:12px;margin-bottom:14px}.section-heading h2{margin:0}.section-heading p{margin:.25rem 0 0;color:var(--muted)}.library-filters{margin-bottom:14px}.summary-strip{padding:10px 12px;border-radius:9px;background:#eef4fa;color:#334e68;margin:12px 0 18px}.cancer-group{margin:20px 0}.cancer-group>h3{margin:0 0 10px;color:var(--navy);font-size:1.02rem}.registry-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(310px,1fr));gap:12px}.regimen-card{border:1px solid var(--border);border-radius:11px;padding:14px;background:#fff}.regimen-card h4{margin:7px 0 4px;color:#173d68}.regimen-card p{margin:3px 0 8px}.regimen-card details{font-size:.83rem;margin-top:8px}.drug-list{display:grid;gap:6px;margin-top:8px}.drug-row{display:flex;justify-content:space-between;gap:12px;background:#f7f9fb;border-radius:7px;padding:7px 9px}.drug-row span{color:#53677b;text-align:right}.manager-actions{display:flex;gap:10px;flex-wrap:wrap;margin:16px 0 22px}.manager-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:12px}.manager-kpi{background:#f6f9fc;border:1px solid #dde7f0;border-radius:10px;padding:16px;display:flex;flex-direction:column}.manager-kpi span,.manager-kpi small{color:var(--muted)}.manager-kpi strong{font-size:1.45rem;color:var(--navy);margin:3px 0}.note-box{margin-top:18px;padding:13px 14px;background:#fff8db;border:1px solid #eadb92;border-radius:9px;color:#624b08}.rounding-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(320px,1fr));gap:14px}.rounding-card{border:1px solid var(--border);border-radius:12px;padding:15px;background:#fbfdff}.compact-grid{margin-top:10px}.prose{max-width:900px}footer{text-align:center;padding:20px;background:#eaf0f6;color:#50657a;font-size:.78rem}@media(max-width:1000px){.three-col{grid-template-columns:repeat(2,1fr)}.result-header,.manager-grid{grid-template-columns:1fr}.topbar{align-items:flex-start}.brand-wrap{align-items:flex-start}}@media(max-width:680px){.form-grid,.three-col,.two-col-grid{grid-template-columns:1fr}.topbar{flex-direction:column}.logo-box img{max-width:70vw}.section-heading{align-items:stretch;flex-direction:column}.drug-row{flex-direction:column}.drug-row span{text-align:left}}@media print{.tabs,.button-row,.prod-badge,footer{display:none!important}body{background:#fff}.topbar{background:#fff;padding:0 0 12px}.card{box-shadow:none}.form-card{border:0;padding:0}.output-card{border:0;padding:0}.logo-box{box-shadow:none}}
.pin-toggle-btn{background:#eef4fa;border:1px solid #cbd9e8;color:#163b66;padding:8px 14px;border-radius:8px;font-weight:700;font-size:.85rem;cursor:pointer;transition:all .2s;display:inline-flex;align-items:center;gap:6px}
.pin-toggle-btn:hover{background:#dbe8f5;border-color:#9eb7d1}
.pin-toggle-btn.unlocked{background:#e7f7ef;border-color:#a8dfc5;color:#146c43}
.rounding-radio-group{display:flex;gap:10px;flex-wrap:wrap;margin:10px 0 16px}
.radio-card{flex:1;min-width:210px;display:flex;align-items:center;gap:10px;background:#f8fafc;border:1.5px solid #d9e2ec;border-radius:9px;padding:10px 14px;cursor:pointer;transition:all .15s ease;font-size:.88rem}
.radio-card:hover{border-color:#9eb7d1;background:#f0f4f8}
.radio-card input[type="radio"]{width:auto;margin:0;accent-color:var(--navy);cursor:pointer}
.radio-card:has(input[type="radio"]:checked){border-color:var(--blue);background:#eef6ff;color:var(--navy)}
#pin-auth-dialog{border:0;border-radius:14px;padding:0;max-width:440px;width:92vw;box-shadow:0 12px 36px rgba(11,44,85,.25);background:#fff}
#pin-auth-dialog::backdrop{background:rgba(11,44,85,.4);backdrop-filter:blur(3px)}
.output-card.has-result{background:linear-gradient(135deg,#f0fdf9 0%,#eef7fc 55%,#f4f9ff 100%)!important;border:1.5px solid #b8dbe8!important;border-radius:16px!important;box-shadow:0 6px 24px rgba(11,44,85,.08)!important;padding:22px!important;transition:all .3s ease}
.output-card.has-result .result-header>div{background:rgba(255,255,255,.9)!important;border:1px solid #c8dfea!important;backdrop-filter:blur(4px);box-shadow:0 2px 6px rgba(11,44,85,.04)}
.output-card.has-result .kpi-label{color:#165b8c!important;font-weight:700}
.output-card.has-result .table-wrap{border:1px solid #bfd8e6!important;background:#fff!important;border-radius:12px;box-shadow:0 2px 8px rgba(11,44,85,.04)}
.output-card.has-result table th{background:#e8f3fa!important;color:#0b2c55!important;font-weight:700;border-bottom:2px solid #cbdfe9}
.output-card.has-result table tr:hover td{background:#f5fafd}
.output-card.has-result table td:nth-child(5){background:#f0faf4!important;color:#11633d!important;font-weight:700}
.search-dropdown{position:absolute;top:calc(100% + 4px);left:0;right:0;max-height:360px;overflow-y:auto;background:#fff;border:1.5px solid #9eb7d1;border-radius:10px;box-shadow:0 12px 32px rgba(11,44,85,.18);z-index:100}
.search-match-item{padding:10px 14px;border-bottom:1px solid #eef2f6;cursor:pointer;transition:background .12s}
.search-match-item:last-child{border-bottom:0}
.search-match-item:hover,.search-match-item.highlighted{background:#eef6ff}
.search-match-title{display:flex;justify-content:space-between;align-items:center;gap:8px}
.search-match-title strong{color:var(--navy);font-size:.95rem}
.search-match-sub{color:#334e68;font-size:.85rem;margin-top:2px}
.search-match-drugs{color:#526a82;font-size:.78rem;margin-top:4px}
.search-empty{padding:14px;color:#627386;text-align:center;font-size:.88rem}